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Diabetologia 1995;38:123

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SR4 upregulated genes involved in Amino acid metabolic process, while downregulating those associated with Glycolysis/Gluconeogenesis, Pyruvate metabolism and the PPP

The resulting fever enhances multiple aspects of the innate and adaptive immune systems5, and creates a suboptimal internal environment that impairs SARS-CoV-2 enzyme function and replication